Story Summary: Signal transduction is in large part controlled by a process called phosphorylation. Drugs are most effective on cancers when they attack the proteins that are activated, he added. While cancers are highly heterogeous in their make-up, the BU researchers believe that a drug that would target this collection of proteins would be effective treatment for most lung cancers. This is the first statistically validated phosphopeptide signature to diagnose any disease, much less cancer or lung cancer, explained senior co-author Martin Steffen, MD, PhD, an assistant professor of pathology and laboratory medicine at BUSM, and director, Proteomics Core Facility at BUSM. Funding for this study was provided by the National Human Genome Research Institute and the American Lung Association. Most of what you read here are press releases from the outfits named in the stories themselves. The other half of the equation is blog postsfrom readers like you. The other half of the equation is blog postsfrom readers like you….Read the Full Story

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