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Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosage

Posted on 27 November 2009 - 14:07 by Alfie

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Story Summary: es34-958-243-534This image shows the effect of gene therapy combined with cytotoxic agents in E spheroids derived from breast cancer cell line MCF-7. So far, attempts to use many chemotherapeutic (cytotoxic) agents similar to the E gene have shown severe limitations resulting from their toxicity and their poor affinity with the tumour. Her work has shown that it is possible to use gene therapy as an aid to chemotherapy, improving its results when it comes to attacking cancer, thus allowing the dosage of agents to be reduced and contributing to a reduction in side effects for the patient. In order to understand how the E gene works, the researchers conducted studies using various techniques. The results of this research suggest the possibility of reducing the concentration of chemotherapeutic agents in current use with cancer patients….Read the Full Story

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