Story Summary: Going from global binding data to CRM activity was a big challenge in the field – one which we have now begun to overcome, says Eileen Furlong, who headed the study. The scientists then trained a computer to unravel the binding profiles for each of these groups, and search the 8000 newly identified CRMs for ones whose binding profiles fitted that picture. Such CRMs were predicted to have similar activity patterns, implying they are involved in regulating the development of the same muscle type. When the scientists tested their predictions experimentally, the results were not only accurate but also enlightening. This plasticity was unexpected, but makes sense in evolutionary terms, the researchers say. The fact that different combinations of transcription factors, or binding codes, can regulate the same developmental process means that even if some transcription factors or CRMs change or are lost during an organisms evolution, it can still develop a gut muscle, for instance. Source: European Molecular Biology Laboratory– 23 July 2009A small green beetle may have some interesting lessons to teach scientists about optics and liquid crystals – complex mechanisms the insect uses to create a shell so strikingly beautiful. — full story– 8 July 2009The Wildlife Conservation Society (WCS) announced today the discovery of a new monkey in a remote region of the Amazon in Brazil….Read the Full Story
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Deciphering the regulatory code
Posted on 09 November 2009 - 09:00 by Alfie
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November 20th, 2009 at 07:38
Deciphering Life’s Regulatory Code
To : Robert P. Zinzen, EMBL Heidelberg
Re : “Deciphering the regulatory code”
A. From “EMBL scientists take new approach to predict gene expression”
http://www.embl.de/aboutus/communication_outreach/media_relations/2009/091104_Heidelberg/index.html
“What’s exciting for me is that this study shows that it is possible to predict when and where genes are expressed, which is a crucial first step towards understanding how regulatory networks drive development”
B. Organism’s behaviour, its reactions to its environments, are “regulatory networks”?
The above statement by Furlong, translated to 22nd century comprehension, amounts to:
What’s exciting is that this study shows that it is possible to predict when and where organisms react to their environments, which is a crucial first step towards understanding how evolution proceeds.
C. Please consider the following suggestions of the origin and nature of life and organisms, and of the origin and nature of cosmic and life evolution
- Genes, Earth’s primal organisms, and all their take-off organisms – Life in general – are but one of the cosmic forms of mass, of constrained energy formats.
- The on-going cosmic mass-to-energy reversion since the Big-Bang inflation is resisted by mass, this resistance being the archtype of selection for survival by all forms of mass, including life.
- The mode of genes’, Earth’s primal organisms, response to the cultural feed-back signals reaching them from their upper stratum take-off organism is “replicate without change” or “replicate with change”. “Replicate with change” is selected in case of proven augmented energy constrainment by the the new generation, this being “better survival”. This mode of Life’s normal evolution is the mode of energy-mass evolution universally.
Suggesting for your consideration,
Dov Henis
(Comments From The 22nd Century)
Updated Life’s Manifest May 2009
http://www.the-scientist.com/community/posts/list/140/122.page#2321
Implications Of E=Total[m(1 + D)]
http://www.the-scientist.com/community/posts/list/180/122.page#3108