Story Summary:…Cholera: disappointing vaccine performance could be caused by worms 16 Apr 2009 Paul Chinnock Cholera vaccines have generally been found to deliver a disappointing performance in the field….However, when given to children in an area of Indonesia endemic for cholera, a rate of only 16% was achieved….The decrease was greatest in the IgA antibodies, which are secreted in the intestine….The finding that worm infection is associated with decreased immune responses to cholera provides an additional reason for deworming in cholera-endemic areas….Read the Full Story

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